Functional evaluation of the P681H mutation on the proteolytic activation the SARS-CoV-2 variant B.1.1.7 (Alpha) spike
B. Lubinski, M. H. Fernandes, L. Frazier, T. Tang, S. Daniel, D. Diel, J. A. Jaimes, G. Whittaker
This study evaluates the impact of the P681H mutation in the SARS-CoV-2 B.1.1.7 spike on furin cleavage and viral entry, finding no significant effect on these processes.
bioRxiv · Apr 6, 2021Microbiology