ImmunologybioRxiv
Human Surfactant Protein D Facilitates SARS-CoV-2 Pseudotype Binding and Entry in DC-SIGN Expressing Cells, and Downregulates Spike protein Induced Inflammation
N. Beirag, C. Kumar, T. Madan…·U. Kishore
This study shows that rfhSP-D enhances SARS-CoV-2 Spike protein binding to DC-SIGN and increases viral uptake in DC-SIGN-expressing cells while reducing inflammation.
DOI 10.3389/fimmu.2022.960733