aPKC-mediated displacement and actomyosin-mediated retention polarize Miranda in Drosophila neuroblasts
M. Hannaford, A. Ramat, N. Loyer, J. Januschke
The paper shows that aPKC phosphorylates Miranda during mitosis, displacing it from the plasma membrane, while actomyosin retention ensures its asymmetric localization in Drosophila neuroblasts.
bioRxiv · Jun 26, 2017Cell Biology