BiophysicsbioRxiv
Nanoscale infrared spectroscopy identifies parallel to antiparallel beta sheet transformation of Aβ fibrils
S. Banerjee, D. Baghel, M. Hasan ul Iqbal, A. Ghosh
This study uses AFM-IR nanospectroscopy to show that Aβ 16-22 transitions from parallel beta sheets to antiparallel fibrils via disordered intermediates, differing from full-length Aβ aggregation.
DOI 10.1021/acs.jpclett.2c02998