Virus-like vesicles expressing multiple antigens for immunotherapy of chronic hepatitis B
T. O. Yarovinsky, S. W. Mason, M. Menon, M. M. Krady, M. Haslip, B. R. Madina, X. Ma, S. Moshkani, C. Chiale, A. Chattopadhyay Pal, B. Almassian, J. K. Rose, M. D. Robek, V. Nakaar
This paper develops virus-like vesicles (VLV) expressing multiple HBV antigens for immunotherapy of chronic hepatitis B, showing 40% efficacy in a mouse model.
bioRxiv · Feb 19, 2019Immunology