White matter changes in the perforant path in patients with amyotrophic lateral sclerosis
Jeroen Mollink, M. Hiemstra, Karla L. Miller, István N. Huszár, Mark Jenkinson, Joost Raaphorst, Maximilian Wiesmann, Olaf Ansorge, Menuka M. Pallebage‐Gamarallage, A.M. van Cappellen van Walsum
This study investigates white matter degeneration in the perforant path of ALS patients using diffusion MRI, polarized light imaging, and immunohistochemistry, finding significant changes in fractional anisotropy and myelin density.
Neuropathology and Applied Neurobiology · Apr 19, 2019Peer-reviewedNeuroscience