Is the production of reactive oxygen and nitrogen species by macrophages associated with better infectious control in the experimental disseminated and pulmonary mucormycosis?
A. R. d. Santos, T. F. Fraga-Silva, D. d. F. A. Donanzam, A. C. Finatto, C. Marchetti, M. I. Andrade, O. S. d. Arruda, M. S. P. d. Arruda, J. Venturini
This study compares macrophage responses in BALB/c and Swiss mice infected with Rhizopus oryzae, finding that higher H2O2 production by peritoneal macrophages correlates with better fungal clearance in resistant mice.
bioRxiv · Jun 6, 2022 · PreprintImmunology