Author

M. I. Lederer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

D. Misiak· 1 shared E. Ghazy· 1 shared J. H. Schulte· 1 shared J. L. Bell· 1 shared M. Haemmerle· 1 shared N. Bley· 1 shared S. Hagemann· 1 shared S. Huettelmaier· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

D. Misiak

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1 paper

Recent·Most cited

IGF2BP1 induces high-risk neuroblastoma and forms a druggable feedforward loop with MYCN promoting 17q oncogene expression

S. Hagemann, D. Misiak, J. L. Bell, T. Fuchs, M. I. Lederer, N. Bley, M. Haemmerle, E. Ghazy, W. Sippl, J. H. Schulte, S. Huettelmaier

This paper identifies a druggable feedforward loop between IGF2BP1 and MYCN in high-risk neuroblastoma that promotes oncogene expression and relapse, suggesting combined targeting as a therapeutic strategy.

bioRxiv · Mar 18, 2023Cancer Biology