Author

M. J. Howard

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. Shanmuganathan· 1 shared B. P. Klemm· 1 shared C. A. Fierke· 1 shared M. Koutmos· 1 shared N. Wu· 1 shared W. H. Lim· 1 shared X. Liu· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. Shanmuganathan

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1 paper

Recent·Most cited

Kinetic mechanism of human mitochondrial RNase P

X. Liu, N. Wu, A. Shanmuganathan, B. P. Klemm, M. J. Howard, W. H. Lim, M. Koutmos, C. A. Fierke

This study investigates the kinetic mechanism of human mitochondrial RNase P, showing that MRPP1/2 enhances catalytic activity and substrate affinity, and facilitates MRPP3 recognition and cleavage efficiency.

bioRxiv · Jun 11, 2019 · PreprintBiochemistry