In vitro tau aggregation inducer molecules influence the effects of MAPT mutations on aggregation dynamics
D. J. Ingham, K. M. Hillyer, M. J. McGuire, T. C. Gamblin
This study shows that different tau aggregation inducer molecules affect how disease mutations alter tau aggregation dynamics, suggesting they produce distinct structural polymorphs.
bioRxiv · Aug 6, 2021Biochemistry