Author

M. J. Shepherd

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

A. P. Pierce· 2 shared T. B. Taylor· 2 shared A. M. Rice· 1 shared M. Reynolds· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersEvolutionary Biology

A. P. Pierce

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2 papers

Recent·Most cited

Regulatory network structure and environmental signals constrain transcription factor innovation

M. J. Shepherd, M. Reynolds, A. P. Pierce, A. M. Rice, T. B. Taylor

The paper shows that high expression levels, not protein homology, determine rewiring potential of transcription factors in Pseudomonas fluorescens.

bioRxiv · May 4, 2023 · PreprintEvolutionary Biology

Evolutionary innovation through transcription factor promiscuity in microbes is constrained by pre-existing gene regulatory network architecture

M. J. Shepherd, A. P. Pierce, T. B. Taylor

The paper shows that transcription factor evolvability is constrained by pre-existing gene regulatory network architecture and identifies properties that enable functional promiscuity in microbes.

bioRxiv · Jul 12, 2022 · PreprintEvolutionary Biology