Author

M. J. Toneff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

M. K. Jolly· 2 shared A. Muruganantham· 1 shared G. Gonzalez· 1 shared H. Levine· 1 shared J. T. George· 1 shared J. Taube· 1 shared K. Mohammad· 1 shared K. S. Johnson· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

M. K. Jolly

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2 papers

Recent·Most cited

Epigenetic memory acquired during long-term EMTinduction governs the recovery to the epithelial state

P. Jain, S. Corbo, K. Mohammad, J. T. George, H. Levine, M. J. Toneff, M. K. Jolly

The paper shows that long-term EMT induction in MCF10A cells can be reversible with longer timescales, and epigenetic memory via miR-200 silencing by ZEB slows recovery to the epithelial state.

bioRxiv · Aug 23, 2022 · PreprintCancer Biology

Epithelial-mesenchymal plasticity through loss of CTCF motif accessibility and protein expression

K. S. Johnson, S. Hussein, P. Chakraborty, A. Muruganantham, S. Mikhail, G. Gonzalez, S. Song, M. K. Jolly, M. J. Toneff, M. L. Benton, Y. C. Lin, J. Taube

The paper investigates chromatin accessibility and CTCF dynamics during reversible EMT/MET, showing CTCF suppression correlates with EMT features and plasticity.

bioRxiv · Jun 8, 2021Cell Biology