Hypercholesterolemia-induced impairment in sorafenib functionality is overcome by avasimibe co-treatment
D. Athavale, H. Yaduvanshi, F. K. Bhati, S. S. Mayengbam, T. More, S. Rapole, M. K. Bhat
This study shows that avasimibe restores sorafenib's anticancer effect in hypercholesterolemia-induced hepatocellular carcinoma by enhancing cytotoxicity and reducing ERK signaling.
bioRxiv · Mar 27, 2024Cancer Biology