Author

M. K. Knowles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Organism:human· 3 Approach:microscopy & imaging analysis· 3 Assay:fluorescence / live-cell microscopy· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Assay:imaging· 1

Frequent Co-Authors

A. W. Weisgerber· 2 shared B. L. Bills· 2 shared Z. Otruba· 2 shared A. Mahmood· 1 shared M. D. Palay· 1 shared M. L. Hulser· 1 shared M. T. Nguyen· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 16 mutual co-author links

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2 shared papersBiophysics

A. W. Weisgerber

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Phospholipase D1 Produces Phosphatidic Acid at Sites of Secretory Vesicle Docking and Fusion

B. L. Bills, M. L. Hulser, M. K. Knowles

This study shows PLD1 produces phosphatidic acid (PA) at secretory vesicle docking and fusion sites, with PA levels decreasing during fusion when PLD1 is inhibited.

bioRxiv · Dec 7, 2023Cell Biology

Syntaxin clusters and cholesterol affect the mobility of Syntaxin1a

A. W. Weisgerber, Z. Otruba, M. K. Knowles

This study investigates the dynamics of Syntaxin1a (Syx1a) mobility on PC12 cells, showing that Syx1a is more mobile within clusters and less so near edges, with cholesterol and the N-terminal Habc domain playing key roles.

bioRxiv · Aug 17, 2023Biophysics

Exosome secretion kinetics are controlled by temperature

A. Mahmood, A. W. Weisgerber, Z. Otruba, M. D. Palay, M. T. Nguyen, B. L. Bills, M. K. Knowles

This study measures exosome secretion kinetics in A549 cells across temperatures and finds that lower temperatures reduce fusion frequency and content loss, with exosomes often tethered post-fusion.

bioRxiv · Jul 22, 2022Cell Biology