Plasmacytoid dendritic cells mediate CpG-ODN induced increase in survival in a mouse model of lymphangioleiomyomatosis
M. Amosu, A. M. Jankowski, J. C. McCright, B. Yang, J. G. d. O. Fernandez, K. Moore, H. S. Gadde, M. Kaluzienski, K. Maisel
This study shows that CpG-ODN improves survival in a mouse LAM model by enhancing immune responses, mediated by plasmacytoid dendritic cells, and synergizes with anti-PD1 and rapamycin.
bioRxiv · Feb 6, 2023Immunology