Controlling load-dependent contractility of the heart at the single molecule level
C. Liu, M. Kawana, D. Song, K. M. Ruppel, J. Spudich
This study measures the load-dependent detachment rate of human β-cardiac myosin at the single molecule level and shows it can be modulated by compounds and mutations.
Nature Structural & Molecular Biology · Jun 4, 2018Peer-reviewedBiophysics