Author

M. Kocan

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Abdul-Ridha· 1 shared A. Gunatilaka· 1 shared A. R. Whitehead· 1 shared D. J. Scott· 1 shared F. Wu· 1 shared L. M. Williams· 1 shared M. Griffin· 1 shared P. R. Gooley· 1 shared

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2019-2019 · peak 1/yr

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1 shared paperBiochemistry

A. Abdul-Ridha

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1 paper

Recent·Most cited

α1A-adrenoceptor inverse agonists and agonists modulate receptor signalling through a conformational selection mechanism

P. R. Gooley, F. Wu, L. M. Williams, A. Abdul-Ridha, A. Gunatilaka, T. M. Vaid, M. Kocan, A. R. Whitehead, M. Griffin, R. A. D. Bathgate, D. J. Scott

This study shows how different ligands modulate the conformational states of the α1A-adrenoceptor through a conformational selection mechanism, as revealed by NMR analysis of labeled receptor mutants.

bioRxiv · Dec 7, 2019 · PreprintBiochemistry