Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors
M. L. Bobby, D. Fearon, M. Ferla, M. Filep, L. Koekemoer, M. C. Robinson, The COVID Moonshot Consortium, J. D. Chodera, A. A. Lee, N. London, A. von Delft, F. von Delft
The paper describes an open-science drug discovery campaign that identified a non-covalent, non-peptidic inhibitor of SARS-CoV-2 main protease using crowdsourcing and computational methods.
bioRxiv · Oct 29, 2020 · PreprintBiochemistry