M. Liss

Direct Cell Extraction of Membrane Proteins for Structure-Function Analysis

The paper develops a method to extract membrane proteins directly from cells into lipid nanoparticles and applies it to study the pannexin1 channel using SPR and cryo-EM.

RBM20 phosphorylation on serine/arginine domain is crucial to regulate pre-mRNA splicing and protein shuttling in the heart

This study identifies phosphorylated residues in RBM20, showing their role in splicing control and protein shuttling, and links their mutation to cardiac dysfunction.