Zinc Dependent Conformational Changes in the Cation Diffusion Facilitator YiiP from S. oneidensis
M. Lopez-Redondo, S. Fan, A. Koide, S. Koide, O. Beckstein, D. L. Stokes
This study examines how Zn2+ binding affects the conformational changes in YiiP from S. oneidensis using cryo-EM and molecular dynamics simulations, revealing an intermediate state and a hydrophobic gate closure mechanism.
bioRxiv · Dec 29, 2020Biophysics