Sustained exposure to trypsin causes cells to transition into a state of reversible stemness that is amenable to transdifferentiation
M. Sharma, R. Kumar, S. Sharma, B. Thomas, G. Kapatia, G. Singh, A. Bal, J. Ram, M. Bhasin, P. Guptasarma, M. Luthra-Guptasarma
This paper shows that sustained trypsin exposure induces cells to transition into a reversible stem-like state, enabling transdifferentiation and altering cellular behavior.
bioRxiv · Jun 23, 2019 · PreprintCell Biology