Defining the chromatin and transcriptional landscape of stem cell-derived islets
P. Augsornworawat, N. J. Hogrebe, M. Ishahak, E. Marquez, M. M. Maestas, M. D. Schmidt, D. A. Veronese-Paniagua, S. E. Gale, J. R. Miller, L. Velazco-Cruz, J. R. Millman
This study uses single-cell multiomic sequencing to analyze chromatin accessibility and transcriptional profiles of stem cell-derived islets, revealing differences in cell identity and chromatin state compared to primary human islets.
bioRxiv · Feb 26, 2022Cell Biology