Author

J. R. Millman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 4 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

L. Velazco-Cruz· 3 shared P. Augsornworawat· 3 shared M. D. Schmidt· 2 shared M. Ishahak· 2 shared A. R. Srivatsava· 1 shared D. A. Veronese-Paniagua· 1 shared E. Marquez· 1 shared J. R. Miller· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersBioengineering

L. Velazco-Cruz

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Comparative and Integrative Single Cell Analysis Reveals New Insights into the Transcriptional Immaturity of Stem Cell-Derived β Cells

M. D. Schmidt, M. Ishahak, P. Augsornworawat, J. R. Millman

This study compares SC-β cells with fetal and adult β cells using single-cell sequencing, finding they share a core β-cell identity but have unique transcriptional profiles with neural-biased gene networks.

bioRxiv · Nov 15, 2023Cell Biology

Defining the chromatin and transcriptional landscape of stem cell-derived islets

P. Augsornworawat, N. J. Hogrebe, M. Ishahak, E. Marquez, M. M. Maestas, M. D. Schmidt, D. A. Veronese-Paniagua, S. E. Gale, J. R. Miller, L. Velazco-Cruz, J. R. Millman

This study uses single-cell multiomic sequencing to analyze chromatin accessibility and transcriptional profiles of stem cell-derived islets, revealing differences in cell identity and chromatin state compared to primary human islets.

bioRxiv · Feb 26, 2022Cell Biology

Assessment of the in vitro function of human stem cell-derived β cells

A. R. Srivatsava, S. T. Shahan, L. C. Gutgesell, L. Velazco-Cruz, J. R. Millman

This study assesses the in vitro function of human stem cell-derived β cells, finding they exhibit increased insulin secretion, cellular respiration, and cytoplasmic calcium ion concentration in response to high glucose.

bioRxiv · May 31, 2019 · PreprintBioengineering

Hydrogel platform for in vitro three-dimensional assembly of human stem cell-derived β cells and endothelial cells

P. Augsornworawat, L. Velazco-Cruz, J. Song, J. R. Millman

This study develops a hydrogel platform to assemble human stem cell-derived β cells and endothelial cells into functional three-dimensional islet organoids.

bioRxiv · May 29, 2019Bioengineering