The pharmacopeia of helminth-derived metabolites driving tolerance in dendritic cells
A. N. Michi, N. L. Malacco, J. A. Sandoval, E. Siciliani, A. G. Madrigal, T. Sternlieb, G. Fontes, I. L. King, I. Cestari, A. Jardim, M. M. Stevenson, T. Hunter, F. Lopes
The paper identifies helminth-derived metabolites that reprogram dendritic cells to a tolerogenic phenotype, reducing intestinal inflammation in mice.
bioRxiv · Jan 26, 2023 · PreprintImmunology