The Theory and Practice of the viral dose in neutralization assay: insights on SARS-CoV-2 "doublethink" effect.
E. Molesti, A. Manenti, M. Maggetti, G. Lapini, A. Torelli, E. Montomoli
This study evaluates the impact of different viral infective doses on micro-neutralization assay results for SARS-CoV-2, finding that a lower dose improves sensitivity without compromising specificity.
bioRxiv · Oct 16, 2020Immunology