A novel effect of the antigenic peptides position for presentation upon MHC class I
J. Imai, M. Otani, E. Koike, Y. Yokoyama, M. Maruya, S. Koyasu, T. Sakai
The paper identifies that N-terminal antigenic peptides are more efficiently presented by MHC-I than C-terminal peptides, linked to rapid degradation of newly synthesized proteins.
bioRxiv · May 29, 2019 · PreprintImmunology