Insulin secretion chip (InS-chip) reveals two peaks within first-phase that temporally coincide with a transition in glucose metabolism.
Y. Wang, R. Regeenes, M. Memon, J. V. Rocheleau
The paper introduces an islet-on-a-chip device (InS-chip) to measure individual islet insulin secretion with high temporal resolution, revealing two glucose-dependent peaks in first-phase secretion linked to metabolic transitions.
bioRxiv · Mar 7, 2023Bioengineering