Fidelity of Prespacer Capture and Processing is Governed by the PAM Mediated Interaction of Cas1-2 Adaptation complex in Escherichia coli
K. N. R. Yoganand, M. Muralidharan, B. Anand
The paper investigates how Cas1-2 in E. coli captures and processes prespacers without Cas4, showing PAM-mediated binding ensures length and PAM conservation.
bioRxiv · Apr 9, 2019Biochemistry