Extracellular endosulfatase Sulf-2 harbours a chondroitin/dermatan sulfate chain that modulates its enzyme activity
R. El Masri, A. Seffouh, C. Roelants, I. Seffouh, E. Gout, J. Perard, F. Dalonneau, K. Nishitsuji, F. Noborn, M. Nikpour, G. Larson, Y. Cretinon, K. Uchimura, R. Daniel, H. Lortat-Jacob, , R. R. Vives
This study identifies a chondroitin/dermatan sulfate chain in Sulf-2 that modulates its enzyme activity, revealing a new paradigm for Sulfs' function.
bioRxiv · Jan 4, 2021 · PreprintBiochemistry