Author

C. Roelants

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

O. Filhol· 2 shared A. Bancet· 1 shared A. Mularoni· 1 shared A. Seffouh· 1 shared C. Battail· 1 shared C. Cochet· 1 shared C. Pillet· 1 shared E. Gout· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

O. Filhol

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2 papers

Recent·Most cited

AB668, a novel highly selective protein kinase CK2 inhibitor with a distinct anti-tumor mechanism as compared to CX-4945 and SGC-CK2-1

A. Bancet, R. Frem, F. Jeanneret, A. Mularoni, P. Bazelle, C. Roelants, J.-G. Delcros, J.-F. Guichou, C. Pillet, I. Coste, T. Renno, C. Battail, C. Cochet, T. Lomberget, O. Filhol, I. Krimm

The paper introduces AB668, a selective CK2 inhibitor with a distinct anti-tumor mechanism compared to CX-4945 and SGC-CK2-1, showing apoptotic effects and pathway stimulation in cancer cells.

bioRxiv · Dec 16, 2022 · PreprintBiochemistry

Extracellular endosulfatase Sulf-2 harbours a chondroitin/dermatan sulfate chain that modulates its enzyme activity

R. El Masri, A. Seffouh, C. Roelants, I. Seffouh, E. Gout, J. Perard, F. Dalonneau, K. Nishitsuji, F. Noborn, M. Nikpour, G. Larson, Y. Cretinon, K. Uchimura, R. Daniel, H. Lortat-Jacob, , R. R. Vives

This study identifies a chondroitin/dermatan sulfate chain in Sulf-2 that modulates its enzyme activity, revealing a new paradigm for Sulfs' function.

bioRxiv · Jan 4, 2021 · PreprintBiochemistry