Role of Strong Localized vs. Weak Distributed Interactions in Disordered Protein Phase Separation
S. Rekhi, D. Sundaravadivelu Devarajan, M. P. Howard, Y. C. Kim, A. Nikoubashman, J. Mittal
This study compares phase separation in intrinsically disordered proteins using two models with different interaction strengths and distributions, finding that distributed interactions promote liquid-like condensates over a broader range of compositions.
bioRxiv · Jan 27, 2023Biophysics