Monitoring alpha-synuclein oligomerization and aggregation using bimolecular fluorescence complementation assays: What you see is not always what you get.
B. Frey, A. AlOkda, M. P. Jackson, N. Riguet, J. A. Duce, H. Lashuel
This study evaluates the reliability of BiFC assays for monitoring alpha-synuclein oligomerization, finding that fluorescent signals do not accurately reflect oligomerization or aggregation.
bioRxiv · May 2, 2020Biochemistry