Author

M. P. Torrens-Spence

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Plant Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:Arabidopsis· 2 Organism:plant (other)· 2 Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

J.-K. Weng· 4 shared C. M. Glinkerman· 2 shared T. Pluskal· 2 shared Y. Wang· 2 shared A. Bobokalonova· 1 shared A. De Abreu· 1 shared A. Shen· 1 shared C. H. Shi· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersBiochemistry

J.-K. Weng

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4 papers

Recent·Most cited

Mechanistic basis for the emergence of EPS1 as a catalyst in plant salicylic acid biosynthesis

M. P. Torrens-Spence, T. Li, Z. Wang, C. M. Glinkerman, J. O. Matos, Y. Wang, J.-K. Weng

The paper identifies how EPS1, a BAHD acyltransferase, evolved to catalyze a unique lyase reaction in SA biosynthesis in Brassicaceae plants through active site reconfiguration.

bioRxiv · Aug 21, 2021 · PreprintBiochemistry

Structural basis for divergent and convergent evolution of catalytic machineries in plant aromatic amino acid decarboxylase proteins

M. P. Torrens-Spence, Y.-C. Chiang, T. Smith, M. A. Vicent, Y. Wang, J.-K. Weng

This paper presents crystal structures of four plant AAAD paralogs, revealing structural features and mutations that underlie divergent substrate selectivity and convergent aldehyde synthase activity evolution.

bioRxiv · Mar 20, 2020Biochemistry

PBS3 and EPS1 complete salicylic acid biosynthesis from isochorismate in Arabidopsis

M. P. Torrens-Spence, A. Bobokalonova, V. Carballo, C. M. Glinkerman, T. Pluskal, A. Shen, J.-K. Weng

This study identifies PBS3 and EPS1 as enzymes completing salicylic acid biosynthesis from isochorismate in Arabidopsis, differing from bacterial pathways.

bioRxiv · Nov 21, 2019Plant Biology

The biosynthetic origin of psychoactive kavalactones in kava

T. Pluskal, M. P. Torrens-Spence, T. R. Fallon, A. De Abreu, C. H. Shi, J.-K. Weng

This study identifies the biosynthetic pathway of kavalactones in kava, revealing key enzymes and enabling heterologous production for psychiatric drug development.

bioRxiv · Apr 4, 2018Plant Biology