Cognitive and molecular characterization of the Ts66Yah murine model of Down syndrome: deepening on hippocampal changes associated with genotype and aging.
C. Lanzillotta, M. Rataj-Baniowska, F. Prestia, C. Sette, V. Nalesso, M. Perluigi, E. Barone, A. Duchon, A. Tramutola, Y. Herault, F. Di Domenico
This study characterizes the Ts66Yah murine model of Down syndrome, revealing genotype-related molecular changes in hippocampal pathways linked to aging and cognitive decline.
bioRxiv · Jan 2, 2024 · PreprintPathology