Epigenetic Control of Adaptive or Homeostatic Splicing of Alternative Exons and Prolactin Gene Expression During Interval-Training Activities of Pituitary Cells
L. Liu, H. Nguyen, U. Das, S. Ogunsola, J. Yu, L. Lei, M. Kung, S. Pejhan, M. Rastegar, J. Xie
This study shows that interval-training depolarization of pituitary cells triggers adaptive or homeostatic splicing of alternative exons, regulated by DNA methylation and MeCP2, while maintaining steady Prolactin gene expression.
bioRxiv · Feb 23, 2024Cell Biology