Single-cell transcriptomes of the aging human skin reveal loss of fibroblast priming
L. Sole-Boldo, G. Raddatz, S. Schuetz, J.-P. Mallm, K. Rippe, A. S. Lonsdorf, M. Rodriguez-Paredes, F. Lyko
The paper uses single-cell RNA sequencing to analyze fibroblast subpopulations in young and old human skin, finding that aging reduces fibroblast priming and alters their interactions with other skin cells.
bioRxiv · May 9, 2019Cell Biology