Only SF3B1 Mutation involving K700E (And Not Other Codons), Independently Predicts Overall Survival in Myelodysplastic Syndromes
R. Kanagal-Shamanna, G. Montalban-Bravo, K. Sasaki, E. Jabbour, C. Bueso-Ramos, Y. Wei, K. S. Chein, T. M. Kadia, F. Ravandi, G. M. Borthakur, K. A. Soltysiak, N. G. Daver, F. Darbaniyan, M. Routbort, K. Patel, , G. Garcia-Manero
This study shows that SF3B1 mutations specifically at codon K700E, but not other codons, are independently linked to better overall survival in myelodysplastic syndromes.
bioRxiv · Sep 4, 2020Cancer Biology