STING activation counters glioblastoma by vascular alteration and immune surveillance
J. V. Joseph, M. S. Blaavand, H. K. Cai, F. Vernejoul, R. W. Knopper, T. B. Lindhardt, K. K. Skipper, E. K. Axelgaard, L. K. Reinert, J. G. Giehm Mikkelsen, P. Borghammer, S. E. Degn, E. Perouzel, H. Hager, B. Hansen, , M. K. Thomsen
This study shows that STING activation reduces glioblastoma progression and prolongs survival by altering tumor vasculature and enhancing immune surveillance.
bioRxiv · Sep 3, 2023Cancer Biology