mRNA induced expression of human angiotensin-converting enzyme 2 in mice for the study of the adaptive immune response to severe acute respiratory syndrome coronavirus 2
M. Hassert, E. Geerling, E. T. Stone, T. L. Steffen, A. Dickson, M. S. Feldman, J. Class, J. M. Richner, J. D. Brien, A. K. Pinto
This study uses mRNA to express human ACE2 in mice to study SARS-CoV-2 adaptive immune responses, finding enhanced T cell responses but no antibody enhancement.
bioRxiv · Aug 7, 2020Immunology