Author

M. S. Laham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Penton· 1 shared G. R. J. Thatcher· 1 shared G. R. Musku· 1 shared H. Lee· 1 shared I. S. Krider· 1 shared J. Fu· 1 shared J. Gordon-Blake· 1 shared K. M. Ratia· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

C. Penton

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1 paper

Recent·Most cited

The mechanism of nicotinamide phosphoribosyltransferase whereby positive allosteric modulation elevates cellular NAD+

K. M. Ratia, Z. Shen, J. Gordon-Blake, H. Lee, M. S. Laham, I. S. Krider, N. Christie, M. S. Ackerman-Berrier, C. Penton, N. G. Knowles, S. R. Musku, J. Fu, G. R. Musku, R. Xiong, G. R. J. Thatcher

This study identifies the mechanism by which NAMPT is activated by positive allosteric modulators, revealing how this enhances NAD+ biosynthesis and regulates NAM binding.

bioRxiv · Oct 21, 2022 · PreprintBiochemistry