Quantitative Profiling Method for Oxylipins in Neurodegenerative Diseases by Liquid Chromatography Coupled with Tandem Mass Spectrometry
E. Pourmand, F. Zhang, M. Sarparast, J. K. Alan, K. S. S. Lee
This paper develops a method to measure CYP-EH PUFA metabolites in C. elegans using UPLC-MS/MS, showing similar metabolites to mammals and demonstrating changes with EH inhibition.
bioRxiv · Oct 2, 2023 · PreprintPhysiology