The CD4 T cell epigenetic JUNB+ state is associated with proliferation and exhaustion
I. S. Mihai, M. Selinger, N. Boucheron, M. N. Forsell, I. Magalhaes, J. Trygg, J. Henriksson
The paper identifies a JUNB+ epigenetic state in CD4 T cells associated with proliferation, exhaustion, and memory formation, and develops a new machine learning tool to analyze its regulation.
bioRxiv · Jan 5, 2024 · PreprintImmunology