Endosomal escape of delivered mRNA from endosomal recycling tubules visualized at the nanoscale
P. Paramasivam, C. Franke, M. Stoeter, A. Hoijer, S. Bartesaghi, A. Sabirsh, L. Lindfors, M. Yanez Arteta, A. Dahlen, A. Bak, S. Andersson, Y. Kalaidzidis, M. Bickle, M. Zerial
The paper visualizes mRNA escape from endosomal recycling tubules using super-resolution microscopy and identifies parameters affecting endosomal escape and cytotoxicity in human cells.
bioRxiv · Dec 18, 2020Bioengineering