A zombie LIF gene in elephants is up-regulated by TP53 to induce apoptosis in response to DNA damage
J. M. Vazquez, M. Sulak, S. Chigurupati, V. J. Lynch
The paper shows that elephants re-functionalized a pseudogene to enhance apoptosis, potentially explaining their resistance to cancer despite large body size.
bioRxiv · Jun 22, 2018Evolutionary Biology