MR1-restricted MAIT cells from the human lung mucosal surface have distinct phenotypic, functional, and transcriptomic features that are preserved in HIV infection
S. Khuzwayo, M. Mthembu, E. W. Meermeier, S. M. Prakadan, S. W. Kazer, T. Bassett, K. Nyamande, D. Fakey Khan, P. Maharaj, M. Mitha, M. Suleman, Z. Mhlane, D. Ramjit, F. Khan, A. K. Shalek, , E. B. Wong
This study identifies distinct phenotypic, functional, and transcriptomic features of MR1-restricted MAIT cells in the human lung mucosa, showing their preservation in HIV infection.
bioRxiv · Nov 19, 2020Immunology