Chiral mismatch in collagen-mimetic peptides modulates cell migration through integrin-mediated molecular recognition
A. Remson, D. Dellemme, M. luciano, M. Surin, S. Gabriele
This study shows that D-chiral collagen-mimetic peptides reduce cell spreading and adhesion by destabilizing integrin interactions, highlighting the role of ECM chirality in cell migration.
bioRxiv · Jul 23, 2024 · PreprintBiophysics