Cancer BiologybioRxiv
USP28 enables oncogenic transformation of respiratory cells and its inhibition potentiates molecular therapy targeting mutant EGFR, BRAF and PI3K.
C. Prieto-Garcia, O. Hartmann, M. Reissland…·M. E. Diefenbacher
This study shows USP28 promotes lung cancer by stabilizing oncogenes and its inhibition enhances therapy for EGFR, BRAF, and PI3K mutant tumors.
DOI 10.1002/1878-0261.13217