SETD3 protein is the actin-specific histidine N-methyltransferase
S. Kwiatkowski, A. K. Seliga, M. Veiga-da-Cunha, D. Vertommen, M. Terreri, T. Ishikawa, I. Grabowska, A. K. Jagielski, J. Drozak
This study identifies SETD3 as the actin-specific histidine N-methyltransferase in vertebrates, showing it methylates β-actin at H73 and affects actin dynamics and glycolytic activity.
bioRxiv · Feb 20, 2018Biochemistry