Toxicogenomic Assessment of In Vitro Macrophages Exposed to Profibrotic Challenge.
J. Morikka, A. Federico, L. Möbus, S. Inkala, A. Pavel, S. Sani, M. Vaani, S. Peltola, A. Serra, D. Greco
This study uses RNA sequencing to analyze immune gene responses in macrophages exposed to bleomycin, identifying dose-dependent gene alterations and linking them to cytokine and proteinase activity.
bioRxiv · Jun 19, 2024Pharmacology & Toxicology