The main activatory and tension-sensitive transitions occur within Prozac sensitive down-states of the potassium selective TREK-2 channel
M. Voldsgaard Clausen, J. Ulstrup, H. Poulsen, P. Nissen
This study identifies two tension-sensitive transitions in TREK-2 channels, showing that the main activation occurs within down conformations, while the down-to-up transition provides additional activation.
bioRxiv · Oct 22, 2020 · PreprintBiophysics